Overview

Airtho partnered with a biotechnology manufacturer to design and deliver a compact, high-performance isolator cleanroom that could be integrated into an existing production space. The project required a modular system capable of achieving ISO 7 cleanliness, efficient recirculation airflow, and precise environmental control—all while fitting around existing equipment and infrastructure.

Challenge

The client needed a fully engineered isolator room within a facility that offered limited overhead space, existing mechanical obstructions, and strict cleanliness requirements. The installation had to support high air-change rates, integrate VRF cooling and makeup air, and provide conditioned and HEPA filtered air—despite the compact footprint and tight coordination zones.

Solution

Airtho engineered a cleanroom system that maximized both performance and constructability:

• High-Efficiency Airflow Design: An Airtho HEPA Hub Kit supplying 84 ACH with eFRM HEPA modules was strategically positioned for maximum performance in process critical areas, outperforming ISO 7 cleanliness specifications.

• Integrated Cooling & Makeup Air: A 2-ton Fujitsu VRF heat pump system supplied conditioned makeup air while supporting room pressurization.

• Modular Architectural System: The cleanroom enclosure incorporated Airtho Modular Wall™ Panels, softwall strip-curtain entries, and a suspended Intelligrid™ ceiling system designed to support HEPA filters, lighting, and blank panels without structural modification to the building.

Results

• Stable ISO 7 cleanroom performance with high-efficiency airflow

• Seamless integration into an existing production environment

• Compact mechanical design supporting high ACH

• Modular ceiling and wall system requiring no major building upgrades

• All proven parts with design, installation management and start-up by Airtho’s project management team